Difference between Pseudogout (CPPD disease) and Gout

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Differences Gout Pseudogout (CPPD Disease)
Causes Excess uric acid in the blood that accumulates in the joint, making deposits of urate crystals. These crystals can trigger inflammation, causing a gout attack. The cause is not known and clearly understood yet. However in general, experts blame the presence of calcium pyrophosphate dihydrate crystals in the affected joint.
Where does it occurs? It occurs more often in the large joint of big toe. However, it can affect other joints, too – such as knee, ankle, mid-foot, and elbows. See more the common and less common joints affected by gout in here! It usually occurs in the knee (mostly) and wrist. However, it can attack any joint, too.
Complications Poorly controlled uric acid in people with gouty arthritis can accumulate in the kidneys and urinary tract, causing kidney stones. See more the link between kidney stones and gout! Poorly controlled pseudogout can cause joint damage that may resemble signs and symptoms of other arthritis types (particularly such as osteoarthritis and rheumatoid arthritis).
The role of diet in the treatment plan Since purine, a protein that can breakdown to become uric acid, can be found in some foods – diet can play a key role in controlling uric acid level in people with gout. See also diet for gout! Diet also has a role to help treat pseudogout and other arthritis forms! But it is not as significant as in gout. Generally, foods that can cause excess inflammation should be restricted by people with arthritis, including if you have pseudogout!
Outlook and prognosis It has better prognosis than other types of arthritis. Even some sufferers never have any flare-up after following the appropriate treatment plan. Overall, it is relatively more treatable than pseudogout.


However, it also can be chronic. Furthermore, chronic gout may cause damage to the joint, too.

Unfortunately, there is currently no cure for pseudogout and it can become chronic condition. In other words, there is a chance for the flares to return.

In general, the goal of the treatment is to help control the disease, treat the symptoms, improve the joint function, prevent the flare-ups, and prevent it from worsening – but not to cure the disease!

In addition, gouty arthritis occurs more often in men. But for CPPD disease, it attacks both women and men equally.

*This article is made for general information only. For more guidance, consult more with a physician /doctor!

Citations /references:

  1. http://www.ouhsc.edu/geriatricmedicine/education/GeriatricRheumatology/pseudogout_fact_sheet.htm
  2. http://www.mayoclinic.org/diseases-conditions/pseudogout/basics/causes/con-20028152
  3. http://www.health.harvard.edu/joint/Diseases_Pseudogout.htm
  4. http://www.nlm.nih.gov/medlineplus/ency/article/000421.htm


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